Micronutrient deficiencies in patients with cirrhosis
DOI:
https://doi.org/10.59093/27112330.112Keywords:
liver cirrhosis, vitamine D, magnesium, zinc, folic acid deficiency.Abstract
Introduction. Vitamin and micronutrient deficiencies are common in patients with cirrhosis and appear to be associated with worse outcomes in the course of the disease. Systematic screening for these deficiencies is not widely practiced in specialized medical consultations, and, therefore, we lack local or regional data that would allow for a more objective approach to this problem. The objective of this research is to determine the prevalence of deficiencies in 25-hydroxyvitamin D, zinc, magnesium, folic acid, and vitamin B12 in patients with cirrhosis at a primary outpatient care center in the Colombian Caribbean. Methodology. This is an observational, retrospective study. Levels of 25-hydroxyvitamin D, zinc, magnesium, folic acid, and cyanocobalamin were extracted from the medical records of patients diagnosed with hepatic cirrhosis from January 2021 to September 2023 at Gastropack SAS. Results. A total of 115 patients were included in the analysis, of whom 68.8% had some type of vitamin or micronutrient deficiency. The most common deficiency was vitamin D, present in 64.3% of patients, followed by deficiencies in magnesium (7%), folic acid (5.2%), vitamin B12 (3.5%), and zinc (0.9%). Conclusion. Vitamin and micronutrient deficiencies are common findings in patients with cirrhosis. Hypovitaminosis D is the most frequently identified deficiency in both compensated and decompensated patients, regardless of the etiology of liver disease.
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