Fulminant liver failure as an unusual presentation of dengue: A case report
DOI:
https://doi.org/10.59093/27112330.119Keywords:
severe dengue, dengue virus, hepatitis, acute liver failure.Abstract
Dengue is one of the most well-known viral diseases worldwide, especially in countries endemic to tropical diseases. It presents a heterogeneous clinical spectrum, ranging from asymptomatic infections to severe cases with multiorgan failure. This case involves a male patient who presented to the emergency department with fever spikes of 3 days' duration and signs of severity compatible with multiorgan dysfunction secondary to severe dengue. The patient showed a significant elevation of transaminases and, after ruling out other probable etiologies, was diagnosed with fulminant hepatic failure. Hepatic involvement should not be overlooked, highlighting the importance of suspecting this condition to make an early diagnosis and promptly initiate appropriate treatments. Managing dengue requires special care and attention, as it is a dynamic disease; therefore, it is necessary to evaluate markers of liver damage and function in patients with dengue.
Downloads
References
Arunpriyandan V, Sundaresan K. Fulminant hepatic failure in dengue fever without plasma leakage: A case report. Cureus 2022; 14:e23964. https://doi.org/10.7759/cureus.23964.
Suganthan N, Sakthilingham G, Kumanan T. Dengue fever complicated with acute liver failure: A case report of expanded dengue syndrome and literature review. SAGE Open Med Case Rep 2020;8:2050313X20913428. https://doi.org/10.1177/2050313X20913428.
Moreno R. Hepatitis fulminante. Rev Gastroenterol México 2013;78:101-102
Trung DT, Thao le TT, Hien TT, Hung NT, Vinh NN, Hien PT, et al. Liver involvement associated with dengue infection in adults in Vietnam. Am J Trop Med Hyg 2010;83:774-780. https://doi.org/10.4269/ajtmh.2010.10-0090.
Faheem M, Osama M, Khurram M, Mujeeb Khan M, Rehman HU, et al. Dengue fever induced fulminant hepatic failure. J Rawalpindi Med Coll (JRMC) 2016;20:331-332.
Dissanayake DM, Gunaratne WM, Kumarihamy KW, Kularatne SA, Kumarasiri PV. Use of intravenous N-acetylcysteine in acute severe hepatitis due to severe dengue infection: A case series. BMC Infect Dis 2021;21:978. https://doi.org/10.1186/s12879-021-06681-9.
Larsen FS, Schmidt LE, Bernsmeier C, Rasmussen A, Isoniemi H, Patel VC et al. High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial. J Hepatol 2016;64:69-78. https://doi.org/10.1016/j.jhep.2015.08.018
Yadav K, Mahay H, Gupta R. Therapeutic plasma exchange as a rescue therapy in three patients of severe dengue with hyperferritinemia and acute hepatic failure: A case series. Int J Surg Med 2019;5:79-82.
Techapornroong M, Kitjarak M, Chetanachan M, Nakaviroj S. Dengue hemorrhagic fever with acute liver failure, a case report with total plasma exchange therapy. J Contin Edu Health Prof 2016;33:230-235.
Nakaviroj S. First case report of high-volume therapeutic plasma exchange as a rescue therapy in dengue hemorrhagic fever with acute liver failure. Chula Med J 2021;65:335-338. https://doi.org/10.58837/CHULA.CMJ.65.3.11.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 The authors retain all copyright and grant the Colombian Association of Hepatology a non-exclusive right to publish and disseminate their work.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Hepatología’s authorship policy is based on the criteria established by the International Committee of Medical Journal Editors (ICMJE) to credit a person for their work while assigning them responsibility for its publication.
| Article metrics | |
|---|---|
| Abstract views | |
| Galley vies | |
| PDF Views | |
| HTML views | |
| Other views | |
